October 17, 2026 11:30 PM
JMA Wireless Dome (Indoors), Syracuse, NY
Louisville
W: 3 L: 3
L5: W L L W W L5 ATS: W L L W W
Spread
-11.5
-114
Moneyline
-521
Game Total
u55.5
-118
at
Syracuse
W: 2 L: 3
L5: L W L L W L5 ATS: W L L L W
Spread
+11.5
-106
Moneyline
+390
Game Total
o55.5
-104
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The matchup between Louisville and Syracuse takes place at JMA Wireless Dome on Saturday October 17 at 7:30 PM. Louisville have won 3 of their last 5 games, and Syracuse have won 2 of their last 5 games.

The Sportsbooks have Louisville as the favorite, with the Moneyline at -529 and the Spread at -11.5. The Game Total line is at 55.5.

Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.

Line Movement

Syracuse Orange - Moneyline
Louisville Cardinals - Moneyline
Syracuse Orange - Spread
Louisville Cardinals - Spread
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