Fact checked at 8:08 AM ET, Nov 13, 2026Odds as of 6:30 AM ET, Nov 13, 2026
DePaul (3-0) visits Northwestern (3-0) at 9:00 PM ET at Welsh-Ryan Arena in Evanston, and neither team has played away from home. DePaul beat West Georgia 75-58, South Florida 82-80 and Alabama A&M 84-47. Northwestern beat Binghamton 86-60, Stony Brook 78-65 and Boston University 72-55 and hasn't trailed for a second. DePaul is a 1.5-point favorite with the total at 139.5. We see it the other way: Northwestern drags this to its own pace and wins a game that ends in the 130s. Two players hang over it. Northwestern forward Jack Karasinski scored 24 in the opener, then missed two games in concussion protocol; his coach sounded optimistic in the latest update but hadn't seen him cleared. DePaul guard Noah Meeusen, its assist leader at 7.5 a game, sat out the Alabama A&M game with an ankle injury his coach says is not long-term, and DePaul hasn't said whether he plays. Men's college basketball has no availability report.
DePaul vs. Northwestern Predictions
Pick #1Northwestern Moneyline+102
The home team is the underdog, and two public projections don't agree with that. One gives Northwestern a 60% chance and the other 68%, an average of about 64%. At +102 the price implies 49.5%. The one projection that prints a score has Northwestern by 2.6, 71-69.
Jake West and LA Pratt are most of the reason. West has scored 20, 23 and 21 with 26 assists, Pratt has 19, 16 and 20, and they carried the last two wins with Karasinski out. Northwestern has turned it over 24 times in three games. It forced 19 turnovers against Boston University, and its three opponents have made 18 of 67 threes.
That three-point defense is the matchup. DePaul has made 34 threes in three games, and Ade Popoola has hit four in each of them. Its easy wins came against West Georgia and Alabama A&M; South Florida lost by only two in Chicago, where DePaul was a 6.5-point favorite. Tonight is DePaul's first road game, possibly without Meeusen, who had eight and seven assists in his two games. Northwestern has also won the last four meetings and eight of the last nine. Bettors agree: 98% of the moneyline money is on Northwestern from 81% of the bets.
A DePaul shooting night like the South Florida game, when it made 14 of 32 threes, would end it. And Northwestern has done all of this at home against weaker teams, so we haven't seen it against anyone this good.
Pick #2Under 139.5−110
Northwestern plays slow, and at home it gets to set the speed. Its box scores work out to about 63 possessions a game, against roughly 70 for DePaul. Its three games finished at 146, 143 and 127 points, each one under the closing total.
Neither defense has given much. Northwestern allowed 60, 65 and 55. DePaul held West Georgia to 58 and Alabama A&M to 47, and its opponents have made 23 of 78 threes. Northwestern's ball security shows up here too: its three opponents have scored nine fast-break points combined.
The projection with Northwestern by 2.6 lands at 140 total points, half a point over. In our view the pace gap pulls it under that. The Under at -110 implies 52.4%, and 62% of the total money is on it from 50% of the bets.
Free throws are the danger. DePaul has taken 72 in three games, and its South Florida game reached 162 points. Karasinski is the other one: if he's cleared, Northwestern gets back a forward who made seven threes in the opener. A fast game full of fouls goes over this number.
21+ (18+ where permitted). Odds subject to change. If you or someone you know has a gambling problem, call 1-800-GAMBLER.
