October 25, 2026 5:00 PM
Mercedes-Benz Stadium (Outdoors), Atlanta, GA
San Francisco 49ers
W: 5
L5:
W
W
W
W
W
L5 ATS:
W
W
L
W
W
at
Atlanta Falcons
W: 2 L: 3
L5:
L
W
W
L
L
L5 ATS:
L
W
W
L
L
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The matchup between San Francisco 49ers and Atlanta Falcons takes place at Mercedes-Benz Stadium on Sunday October 25 at 1:00 PM.
San Francisco 49ers have won 5 of their last 5 games, and Atlanta Falcons have won 2 of their last 5 games.
The Sportsbooks have San Francisco 49ers as the favorite, with the Moneyline at -220 and the Spread at -4.5.
The Game Total line is at 49.5.
Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.
Best Bets from the OddsCrowd algorithm
OddsCrowd Algorithm uses advanced data monitoring and analytics to identify value driven picks. It aggregates the odds and line movements of the most advanced sportsbooks in the world to calculate what it deems the ‘perfect odds’ for every matchup. When the algorithm finds Odds by Legal US Sportsbooks that it determines offer value relative to it’s perfect odds, it recommends the bet. This is what is commonly referred to as +EV or ‘ Plus Expected Value’ betting. Please be aware that these picks are time sensitive due to odds & line movements.
Atlanta Falcons +4.5
-110
Spread (Full Game)