October 21, 2026 11:30 PM
KeyBank Center (Indoors), Buffalo, New York
Philadelphia Flyers
W: 1 L: 6
L5: W L L L L L5 ATS: W W L L L
at
Buffalo Sabres
W: 4 L: 3
L5: L W L W L L5 ATS: L W W W L
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The matchup between Philadelphia Flyers and Buffalo Sabres takes place at KeyBank Center on Wednesday October 21 at 7:30 PM. Philadelphia Flyers have won 1 of their last 5 games, and Buffalo Sabres have won 2 of their last 5 games.

The Sportsbooks have Buffalo Sabres as the favorite, with the Moneyline at -152 and the Spread at -1.5. The Game Total line is at 5.5.

Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.

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Buffalo Sabres - Moneyline
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