October 4, 2026 5:00 PM
Highmark Stadium (Outdoors), Orchard Park, NY
New England Patriots
Money: 77% Public: 52%
W: 1 L: 2
L5: L W L L W L5 ATS: L W W L W
Spread
+6.5
-104
Moneyline
+270
Game Total
u47.5
-105
at
Buffalo Bills
Money: 22% Public: 47%
W: 3
L5: W W W W W L5 ATS: L W W W L
Spread
-7
-105
Moneyline
-312
Game Total
o48.5
-105
Game Preview
Best Odds
Enter Picks

The matchup between New England Patriots and Buffalo Bills takes place at Highmark Stadium on Sunday October 4 at 1:00 PM. New England Patriots have won 2 of their last 5 games, and Buffalo Bills have won 5 of their last 5 games.

The Sportsbooks have Buffalo Bills as the favorite, with the Moneyline at -325 and the Spread at -6.5. 47% of the Public’s wagers at the Spread have been on Buffalo Bills. The Game Total line is at 48.5.

Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.

Best Bets from the OddsCrowd algorithm

OddsCrowd Algorithm uses advanced data monitoring and analytics to identify value driven picks. It aggregates the odds and line movements of the most advanced sportsbooks in the world to calculate what it deems the ‘perfect odds’ for every matchup. When the algorithm finds Odds by Legal US Sportsbooks that it determines offer value relative to it’s perfect odds, it recommends the bet. This is what is commonly referred to as +EV or ‘ Plus Expected Value’ betting. Please be aware that these picks are time sensitive due to odds & line movements.
2.1% + EV Edge
Under 48.5
-110
Total (Full Game)
7.2% + EV Edge
New England Patriots
+270
Moneyline (Full Game)

Public Money

+257
moneyline
15%
bets
10%
money
-5%
diff
-325
moneyline
84%
bets
89%
money
+5%
diff
+6.5
spread
52%
bets
77%
money
+25%
diff
-6.5
spread
47%
bets
22%
money
-25%
diff
Over
48.5
total
53%
bets
83%
money
+30%
diff
Under
48.5
total
46%
bets
16%
money
-30%
diff

Line Movement

Buffalo Bills - Moneyline
New England Patriots - Moneyline
Buffalo Bills - Spread
New England Patriots - Spread
Total

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