October 4, 2026 8:25 PM
Levi's Stadium (Outdoors), Santa Clara, CA
Denver Broncos
Money: 51%
Public: 58%
W: 2 L: 1
L5:
W
W
L
W
L
L5 ATS:
W
W
W
W
L
at
San Francisco 49ers
Money: 48%
Public: 41%
W: 3
L5:
W
W
W
W
W
L5 ATS:
L
W
W
W
W
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Best Odds
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The matchup between Denver Broncos and San Francisco 49ers takes place at Levi's Stadium on Sunday October 4 at 4:25 PM.
Denver Broncos have won 3 of their last 5 games, and San Francisco 49ers have won 5 of their last 5 games.
The Sportsbooks have San Francisco 49ers as the favorite, with the Moneyline at -151 and the Spread at -2.5.
41% of the Public’s wagers at the Spread have been on San Francisco 49ers.
The Game Total line is at 46.5.
Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.
Best Bets from the OddsCrowd algorithm
OddsCrowd Algorithm uses advanced data monitoring and analytics to identify value driven picks. It aggregates the odds and line movements of the most advanced sportsbooks in the world to calculate what it deems the ‘perfect odds’ for every matchup. When the algorithm finds Odds by Legal US Sportsbooks that it determines offer value relative to it’s perfect odds, it recommends the bet. This is what is commonly referred to as +EV or ‘ Plus Expected Value’ betting. Please be aware that these picks are time sensitive due to odds & line movements.
Denver Broncos +2.5
+100
Spread (Full Game)