Steelers vs. Bengals NFL Week 7 TNF Best Picks

Thursday Night Football in Week 7 of the 2025 NFL season is a showdown in the AFC North between the Pittsburgh Steelers and Cincinnati Bengals. This is a tale of two division rivals going in different directions. Pittsburgh is 4-1 and has won three games in a row, while an injury-plagued Cincinnati squad is 2-4 and mired in a four-game losing streak.

With Thursday’s contest set for 8:15 pm ET on Amazon Prime, it’s time to break down the odds and discuss the best bets to make. 

Steelers vs. Bengals Predictions 

Pick #1: Pittsburgh Steelers -5.5 (-112) vs. Cincinnati Bengals Click Here to Bet

Pick #2: Pittsburgh Steelers vs. Cincinnati Bengals Under 42.5 (-105) Click Here to Bet

Pick #3: Jaylen Warren Over 52.5 Rushing Yards (-114) Click Here to Bet

PICK #1: Steelers -5.5 (-112) vs. Bengals (-112) Click Here to Bet

This is a fantastic spot for the Steelers. Not only do they have a lot of momentum, but they have also played only one game since September 28, after benefiting from a bye in Week 5. This past Sunday’s contest was a walk in the park against Cleveland, as Pittsburgh prevailed 23-9 and never came close to trailing at any point. Head coach Mike Tomlin’s team is healthy, well-rested and enjoying life atop a surprisingly lopsided AFC North in which every other club has been a complete disaster in 2025.

That includes the Bengals, for whom it has all gone south since Joe Burrow suffered a foot injury that will sideline him for at least three months. The quarterback play was so bad thereafter, with Jake Browning under center, that Cincinnati traded for 40-year-old Joe Flacco, who started this past weekend. Cincy was relatively competitive during a 27-18 loss to Green Bay, but Flacco averaged a mere 4.9 yards per attempt and the visitors rushed for only 55 yards. Things don’t figure to improve on the offensive side of the ball against T.J. Watt and a Pittsburgh defense that is tied for second in the NFL with 20 sacks. 

PICK #2: Steelers vs. Bengals Under 42.5 (-105) Click Here to Bet

This total is too high for a game involving a 40-year-old quarterback matched up against a formidable defense. In five games this season (four with Cleveland), Flacco has thrown more interceptions (six) than touchdowns (four) and is completing only 59.5% of his passes.

Cincinnati’s running game has also been anemic. Chase Brown is averaging just 2.7 yards per attempt, gaining 202 yards on 74 carries while scoring only one touchdown. As for the Steelers’ offense, Aaron Rodgers has been solid so far in 2025 – but at 41 years old, he no longer brings any explosiveness to the table. The combined age of the two QBs in this game is 81; you have to like the Under.

PICK #3: Jaylen Warren Over 52.5 Rushing Yards (-114) Click Here to Bet

Warren has not gotten entirely on track yet this season, but he missed Week 4, and then his whole team was off in Week 5. A bunch of rest seemed to do him plenty of good, as the Oklahoma State product came back and rushed for 52 yards on just 11 carries (4.7 average) against the Browns, who allow the third-fewest rushing yards per game.

Warren figures to get a larger volume of work this coming Sunday, as the likely game script calls for the Steelers to seize a quick lead and then milk the clock the rest of the way. That’s not to say that Rodgers is not going to sling the ball around at all, but Pittsburgh is a run-first team that should certainly be the case in this particular matchup. The Bengals are No. 28 in the NFL against the run, giving up 135.7 yards per game.