Falcons vs Colts NFL Week 10 Best Picks in Berlin

Sunday’s slate in Week 10 of the 2025 NFL season will kick off bright and early in Berlin, Germany, with a matchup at 9:30 AM ET on NFL Network. The Atlanta Falcons take on the Indianapolis Colts in a matchup between two teams coming off difficult losses. The Colts suffered their second loss of the season to the Steelers in Week 9, while the Falcons come into this one following a one-point loss to the Patriots on the road, with Atlanta losing on a missed extra point in that contest. 

Which team will come out on top in this inter-conference matchup? Let’s get into our Falcons vs Colts best bets for Sunday.

Falcons vs Colts predictions

• Pick #1: Atlanta Falcons +6.5 (-110) vs Indianapolis Colts
• Pick #2: Under 48.5 Total Points (-110)
• Pick #3: Jonathan Taylor Over 18.5 Rush Attempts (-120)

PICK #1: Falcons +6.5 (-110) vs Colts

Ordinarily, this would be a spot in which we’d look to back the Colts, given that Indianapolis is coming off a loss in which it turned the ball over five times and should be primed for a bounce-back performance as a result. However, even with RB Jonathan Taylor to lean on in the backfield, this is a bit of a tricky spot for the Colts, given the overseas travel.  

The Colts offense came back down to earth a bit in last week’s loss to the Steelers, as QB Daniel Jones turned the ball over five times and Indianapolis struggled to finish drives. While we’re not convinced that is going to be a sign of things to come, Indianapolis was certainly due for a bit of regression, given the fact that this offense was profiling as one of the best units of all time through the first half of the season. Look for the Falcons' secondary to keep the Colts' passing game in check, which should keep this game within one score. 

PICK #2: Under 48.5 Total Points (-110)

Atlanta keeping this game within six points pairs nicely with the Under, especially since games overseas have the tendency to be lower-scoring. While most experts believed that the Falcons offense would be the strength of their team heading into this season, that has not been the case thus far. In fact, Atlanta’s defensive front has done a really good job of getting pressure on its opponents, and the Falcons' pass defense has been the best in football (158.1 passing yards allowed per game). 

On the other side of the ball, the Atlanta offense has struggled with consistency of late, particularly on the ground, as All-Pro RB Bijan Robinson has tallied just 40, 25 and 46 rushing yards over the past three games. The Colts' secondary is also getting a major boost via the addition of Sauce Gardner at cornerback, so don’t expect a high-scoring effort from Atlanta in Berlin on Sunday. 

PICK #3: Jonathan Taylor Over 18.5 Rush Attempts (-120)

While this is not a number that Jonathan Taylor has cleared all that much this season, this week’s game is a bit of a different circumstance. Atlanta has an excellent pass defense, and Daniel Jones is coming off his worst game of the season by far. Furthermore, this one projects to be a one-score game late into the contest, which means the Colts will likely be turning to Taylor to help either take the lead or salt the game away in the final minutes. Let’s back the MVP candidate to shoulder a heavy workload in this one.