Commanders vs Packers NFL Week 1 TNF Picks

The second week of the 2025 NFL season begins with a prime-time showdown at one of the most iconic venues in football. The Green Bay Packers welcome the Washington Commanders to Lambeau Field for Thursday Night Football, and both teams come in with momentum after notching wins in Week 1. It's early in the season, but this game could say a lot about where each team is headed.

Kickoff is at 8:15 PM ET, and fans will be tuning in on Prime Video, with the veteran broadcast duo of Al Michaels and Kirk Herbstreit on the call. These early-season matchups can be tricky to predict, but with two young, talented rosters and a national spotlight, expect both teams to come out swinging.

Let’s break down the game and take a look at our experts' three best bets and predictions ahead of Thursday night’s action.

Commanders vs Packers Predictions

Pick #1 – Packers -3.5 (-110) over Commanders Click Here to Bet

Pick #2 – Game Total Under 48.5 Points Click Here to Bet

Pick #3 – Josh Jacobs (+100) Anytime Touchdown Click Here to Bet

Pick #1: Packers -3.5 over Commanders (-110)

The Packers looked confident and cohesive in their season opener, and they now return to Lambeau — a place that consistently ranks as one of the toughest stadiums for road teams to play. Quarterback Jordan Love showed a solid command of the offense, while running back Josh Jacobs provided a physical presence in the run game that helped wear down Detroit in Week 1.

Washington, to their credit, also started the season strong. Jayden Daniels, entering his second year, looked comfortable and showed signs of progression. But facing this Green Bay defense on a short week and on the road is a much tougher challenge.

One key storyline? Micah Parsons. The Packers' newest defensive weapon made an immediate impact in his Green Bay debut, racking up a sack and bringing consistent pressure. If he and Rashan Gary can collapse the pocket, Daniels might struggle to find rhythm — especially behind a Washington offensive line that still has question marks.

Given all that, backing the Packers to cover the 3.5-point spread at home feels like the right move. They’re the more complete team right now, and Lambeau gives them a significant edge.

Pick #2: Game Total Under 48.5 Points (-110)

It’s no secret: Thursday Night Football games are often slow-paced and lower scoring — especially in the early part of the season. Teams have just a few days to prepare, which typically leads to simplified game plans and conservative play-calling.

Defensively, both squads impressed in Week 1. The Packers held the Lions to just 13 points, while Washington’s defense completely shut down the Giants, allowing only six points. Neither offense is built for a shootout, especially when factoring in the short week and tough opposing defenses.

Green Bay's pass rush, spearheaded by Parsons and Gary, could create real problems for Daniels, particularly if Washington is forced into obvious passing downs. On the flip side, Green Bay’s offense, while promising, is still young and inconsistent at times. Washington’s defensive front is good enough to create some disruption and possibly force a few stalled drives.

All it might take is a few key red zone stops or a couple of penalties to keep this game from reaching 49 points. Betting the Under feels like a sharp play in what could turn into a gritty, defensive battle.

Pick #3: Josh Jacobs Anytime Touchdown (+100)

When it comes to finding value in player props, Josh Jacobs to score a touchdown stands out as one of the safest options. He reached the end zone in Week 1, marking his ninth straight game with a touchdown dating back to the 2024 season.

The Packers clearly trust Jacobs near the goal line. Whether it’s a third-and-short carry or a red zone screen pass, he’s the guy they lean on in key situations. He might not be a 25-touch workhorse anymore, but he doesn’t need to be; he just needs the right touches.

At +100 odds, you’re getting even money on a player who consistently produces when it matters most. In what should be a competitive, physical game, Green Bay will likely rely on Jacobs to punch it in if they get into scoring position.