November 7, 2026 12:00 AM
Littlejohn Coliseum (Indoors), Clemson, SC
weather
64.1ºF
Wind: 1.7mph NNE
American
L: 1
L5: L L L L W L5 ATS: L L L L W
Spread
+17.5
-110
Moneyline
+1400
Game Total
u143
-110
at
Clemson
W: 1
L5: W L L W W L5 ATS: L L L L W
Spread
-17.5
-110
Moneyline
-2778
Game Total
o144.5
-105
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The matchup between American and Clemson takes place at Littlejohn Coliseum on Friday November 6 at 7:00 PM. The Sportsbooks have Clemson as the favorite, with the Moneyline at -3448 and the Spread at -17.5. The Game Total line is at 144.5.

Read further below for the best betting picks from the OddsCrowd community and more important stats and insights. Use the other tabs to see the best odds from the legal US sportsbooks and track your betting picks.

Line Movement

Clemson Tigers - Moneyline
American Eagles - Moneyline
Clemson Tigers - Spread
American Eagles - Spread
Total

Schedule

AMER
Head-to-Head
CLEM
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ATS
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